Study on Dissolution Determination Method of Boling Dripping Pills
- VernacularTitle:波棱滴丸溶出度的测定方法研究
- Author:
Huan XIE
- Publication Type:Journal Article
- Keywords:
Boling dripping pills;
Herpetin;
Dissolution
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish a method for the dissolution determination of Boling dripping pills.Methods With 0.5 % sodium dodecylsulfate as solvents and rotation speed being 100 r/min,a RP-HPLC method was used to deter- mine the content of herpetin with the detection wavelength of 280 nm.Results Herpetin showed a good linear relationship with peak area in the range of 0.084～1.008?g(r=0.9999),and the average recovery was 99.18% and RSD was 2.15 %.The dissolution of three batches was 87.3 %～90.8 %.Conclusion This method is simple,accurate,reliable and suitable for the quality control of Boling dripping pills.
