Formula and process optimization of Danggui Buxue Pellets prepared by extrusion-spheronization
- VernacularTitle:挤出滚圆法制备当归补血微丸的处方及工艺优化
- Author:
Hongxia CHEN
- Publication Type:Journal Article
- Keywords:
Danggui Buxue Formula;
extrusion-spheronization;
pellet;
micromeritic properties
- From:
Chinese Traditional Patent Medicine
1992;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To prepare traditional Chinese medicine formula Danggui Buxue Pellets by extrusion-spheronization and to study the optimal process and formulation. METHODS: Danggui Buxue Pellets were prepared by a new style extrusion-spheronization equipment;The optimal process and formulation were obtained on the studies of influenitial factors and L_9(3~4) orthogonal design,The micromeritic properties and reception percentage of pellets were determined. RESULTS: The prepared Danggui Buxue Pellets by extrusion-spheronization were all spheral with smooth surface;The percent of reception was not less than 85%. CONCLUSIONS: Extrusion-spheronization is suitable to produce herbal medicine pellets.The preparation process is simple and feasible;The quality of the prepared pellets is excellent and the percent of reception is high.
