Protective effect of Xiaoyan Lidan Tablet on acute hepatic injury in rats
- VernacularTitle:消炎利胆片防治大鼠急性肝损伤的实验研究
- Author:
Murong YE
;
Yukiko NAGAO
;
Chuyuan LI
;
Deqin WANG
;
Jiannan CHEN
;
Xiaoping LAI
- Publication Type:Journal Article
- Keywords:
Xiaoyan Lidan Tablet;
carbon tetrachloride;
D-galactosamine;
acute hepatic injury;
rats
- From:
Chinese Traditional Patent Medicine
1992;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study the protective effects of Xiaoyan Lidan Tablet(Herba Andrographis,Herba Rabdosiae serrae,Radix Sophorae Flavescentis,etc) on acute hepatic injury in rats. METHODS: Acute hepatic injury was induced by intraperitoneal(ip) injection of carbon tetrachloride and D-galactosamine,respectively.The levels of ALT,AST,ALP,TBA,total bilirubin(T-Bil),total protein (TP) and albumin(ALB) in serum were analyzed.The body weight,liver weight,spleen weight and thymus weight of each rat were measured.The hepatic glycogen content was analyzed individually.Liver tissue pathology was observed. RESULTS: Xiayan Lidan Tablet can decrease ALT,AST,ALP,TBA and T-Bil in serum,reduce necrosis in pathological observation. CONCLUSION: Xiaoyan Lidan Tablet gives the protective effects to acute hepatic injury induced by CCl_4 and D-Gal in rats.
