Study on the Association between G-protein ?3 Subunit Gene Polymorphism and the Emotion Trait of Chest Stuffiness and Pains Patients
- VernacularTitle:G蛋白?3亚单位基因多态性与胸痹心痛患者情志因素的关联性分析
- Author:
Yingchun ZHOU
;
Yifen WU
- Publication Type:Journal Article
- Keywords:
chest stuffiness and pains;
depression;
G-protein ?3 subunit;
polymorphism
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between polymorphism of G-protein ?3 subunit (GNB3) gene and the emotion trait of chest stuffiness and pains patient. Methods The GNB3 gene type in 27 patients of depression of chest stuffiness and pains, 40 patients of no depression of chest stuffiness and pains, and 20 patients of healthy subjects (control) was determined by polymerase chain reaction and restriction fragment incision enzyme, and score of depression was evaluated. Result Occurrence of depression in chest stuffiness and pains was significantly higher than that in control (P