Influence of Complex Prescription of Replenishing Qi,Activating Blood and Resolving Phlegm on the Levels of LN and PC-Ⅲ in BALF in Rat Model of Pulmonary Fibrosis
- VernacularTitle:益气活血化痰方对肺纤维化大鼠支气管肺泡灌洗液中层粘连蛋白、Ⅲ型前胶原含量的影响
- Author:
Shuwen GUO
;
Guohua WANG
;
Panchu YANG
- Publication Type:Journal Article
- Keywords:
pulmonary fibrosis;
LN;
PC-Ⅲ;
replenishing Qi, activating blood and resolving phlegm
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effects of complex prescription with the effects of replenishing Qi, activating blood and resolving phlegm on the levels of LN and PC-Ⅲ in BALF and the changes of lung tissue and figure in rat with pulmonary fibrosis. Method The rat model of pulmonary fibrosis was established by injecting pinyamycin, then the changes of the levels of LN and PC-Ⅲ in every group (TCM group, model group and control group) in 7, 28 days respectively were observed. Result There was obvious pulmonary fibrosis morphologic change. Lung quotient increased clearly, and the levels of LN and PC-Ⅲ in BALF increased obviously in 28 days (P