Predictive Value of Human Papillomavirus Detection for Precancerous Lesions of Uterine Cervix
- VernacularTitle:人乳头瘤病毒感染量测定对宫颈癌前病变预测意义的探讨
- Author:
Runying YE
;
Juan ZHANG
;
Jianling HAUNG
- Publication Type:Journal Article
- Keywords:
HUMAN PAPILLOMAVIRUS;
CERVICAL NEOPLASM;
PRECANCEROUS LESIONS;
HPV-DNA QUANTITATIVE DETECTION
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2004;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】To explore the relationship of precancerous lesions of uterine cervix with human papillomavirus(HPV)DNA content in high risk women detected by the method of hybrid capture Ⅱ(HC2).【Methods】From September of 2003 to January of 2005,433 outpatients were collected in gynecology department of the Second Affiliated Hospital of Guangzhou University of TCM.Cervical HPV-DNA contents were detected by HC2.For those with HPV-DNA positive,Thinprep cytologic test(TCT)was done and further examination under colposcope such as multiple cervical biopsy and endocervical scraping smear was performed if TCT showed abnormalities of cytology.【Results】There were 128 patients with HPV-DNA positive,and 98(76.56%)with abnormal cytologic changes such as atypical squamous cell of undetermined significance(ASCUS),low-grade squamous intraepithelial lesion(LSIL)and high-grade squamous intraepithelial lesion(HSIL),which was more than those(23.44%)with normal cervical cells.For the patients with abnormalities of cytology,HPV-DNA content was higher than those with normal cervical cells(P
