Clinical observation of neutrophil adhesion molecules expression during coronary artery surgery under cardiopulmonary bypass
- VernacularTitle:体外循环下冠状动脉旁路移植术中性粒细胞表面黏附分子表达水平的临床观察
- Author:
Wei ZHAO
;
Chenghui LI
;
Naiguang JIA
- Publication Type:Journal Article
- Keywords:
Coronary artery bypass Reperfusion injury Troponin I Antigens,CD11
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
1995;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the changes of CD11b on neutrophils during myocardial ischemia-reperfusion injury. Methods 12 patients undergoing coronary bypass grafts under CPB were studied. Blood samples were obtained from the coronary (coronary sinus) and systemic circulation (central venous and CPB machine), respectively. Samples obtained from coronary and systemic circulation were taken before the beginning of CPB, during CPB and after cardiac reperfusion. Neutrophil CD11b expression and serum cTnI concentration were measured. Results (1)Expression of CD11b increased gradually in systemic circulation during CPB and after reperfusion (P
