Effect of Jinkui Shenqi Pill on 17?-hydroxylase Gene Expression in Kidney Yang Deficiency Rats
- VernacularTitle:金匮肾气丸对肾阳虚大鼠17?-羟化酶基因表达的影响
- Author:
Dongsheng ZHENG
;
Xiaowei ZHENG
- Publication Type:Journal Article
- Keywords:
JGSQP;
kidney yang deficiency;
adrenal;
17?-hydroxylase;
gene expression
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of Jinkui Shenqi pill (JKSQP) on 17?-hydroxylase gene expression in kindney yang deficiency rats. Methods The rats were randomly divided into normal group, tmodel group and JKSQP group. Animal model of kidney yang deficiency was built by adenine. Reverse transcriptase polymerase chain reaction (RT-PCR) was used to observe the effect of JKSQP on 17? -hydroxylase mRNA of adrenal tissue in rats treated at different time points (10, 20, 30 d). Results As compared with the model group, JKSQP can increase gene expression of 17?-hydroxylase in the adrenal of rats (P
