Experimental Study of Sanshanxiao Granules on the Levels of Insulin and Lipid Peroxidation in Model Rats of Diabetes
- VernacularTitle:三山消颗粒对糖尿病大鼠胰岛素水平及脂质过氧化反应的影响
- Author:
Zhiyan LU
;
Yuyun HUANG
;
Nianping ZHANG
- Publication Type:Journal Article
- Keywords:
diabetes;
Sanshanxiao granules;
insulin;
free radicals
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study pharmacological mechanism of Sanshanxiao granules in treating diabetes. Methods The rat model of diabetes was set up by injecting STZ intraabdominally. The modeled diabetic animals were divided into model group, Sanshanxiao group, and Xiaokewan control group. Normal rats were devised as blank-contrasted group. It was observed through several aspects on the level of blood sugar and insulin, activity changes of SOD in serum, contents of MDA and changes of islets of pancreas morphologic contrastly. Results Sanshanxiao granules can reduce blood sugar, stimulate insulin secreted, develop activity of SOD and decrease the contents of MDA obviously (P
