Transformation of alisol B 23-acetate in processing of Alisma orientalis
- VernacularTitle:泽泻炮制过程中23-乙酰泽泻醇B的转化
- Author:
Yunfeng ZHENG
;
Yulan ZHU
;
Guoping PENG
- Publication Type:Journal Article
- Keywords:
Alisma orientalis (Sam.) Juzep. triterpenes;
alisol A 24-acetate;
alisol B;
alisol B 23- acetate;
alisol A;
processing
- From:
Chinese Traditional and Herbal Drugs
1994;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the transformation mechanism of triterpenes in processing of Alisma orientalis. Methods The triterpene transformations of A. orientalis pre and post-processing were comparatively analyzed by techniques of HPLC and Packed Column Supercritical Fluid Chromatography (SFC). Results In baked processing (70 ℃) of A. orientalis, little alisol B 23-acetate was transformed into alisol A 24-acetate and alisol B.However, more alisol B 23-acetate was transformed into alisol A 24-acetate and alisol B, then both of them were further transformed into alisol A in processing under high temperature (160-200 ℃). Conclusion Transformation of alisol B 23-acetate has two routes when A. orientalis is processed under high temperature: For one, alisol B 23-acetate is rearranged into alisol A 24-acetate which could be deacetylated into alisol A; for the other; it is deacetylated into alisol B first, then transformed into alisol A.
