Effect of Huangqin Zhengqi Capsule on Gastrointestinal Function in Rats with Syndrome of Damp Retention in Middle-jiao
- VernacularTitle:黄芩正气胶囊对湿阻中焦证大鼠模型胃肠功能的影响
- Author:
Xianghua KONG
;
Xia WANG
;
Hai HUANG
- Publication Type:Journal Article
- Keywords:
Huangqin Zhengqi Capsule;
Syndrome of damp retention in middle-jiao;
Animal model;
Gastrointestinal function
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the therapeutic mechanism of Huangqin Zhengqi Capsule(HZC)for the syndrome of damp retention in middle-jiao.Methods The rat model of damp retention in middle-jiao was established according to the literature.HZC was administered by gastric gavage in the dosage of 0.175,0.350 and 0.700 g/kg.After treatment,the serum gastrin content,small intestinal absorbency to D-xylose,small intestinal peristalsis,activities of gastric mucosal protective factors such as superoxide dismutase (SOD) and catalase(CAT)as well as gastric pathologic changes were observed.Results HZC can obviously increase serum gastrin content,increase small intestinal absorbency to D-xylose and peristalsis of small intestine,increase the activities of SOD and CAT,as well as improve the gastric pathologic changes in model rats(P
