Antioxidation Effect of Citrus Flavonoids on Aged Mice Induced by D-galactose
- VernacularTitle:柑橘黄酮对D-半乳糖衰老模型小鼠抗氧化作用
- Author:
Bei LU
;
Lingjing YE
;
Wenqin YAN
;
Xiaohong XU
- Publication Type:Journal Article
- Keywords:
Citrus flavonoids;
D-galactose;
Antioxidation
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the in-vivo antioxidation effect of citrus flavonoids.Methods The aged mice were induced by subcutaneous injection of D-galactose (1 g?kg-1?d-1)for 6 weeks and simultaneously received gastric infusion of citrus flavonoidsat at different dosages(200 mg?kg-1?d-1 or 600 mg?kg-1?d-1)for 6 weeks.After treatment,the SOD activity and the MDA content in liver and skin as well as the content of hydroproline (HYD) in skin were measured.Results Citrus flavonoids increased the SOD activity significantly (P