Study on Effects and Mechanism of Huoluojiangu Capsule on Adjuvant Arthritis Rats
- VernacularTitle:活络健骨胶囊对佐剂性关节炎大鼠的作用及机制研究
- Author:
Jiamao ZHOU
;
Fengxiang YAN
;
Jianshe QUAN
- Publication Type:Journal Article
- Keywords:
Huoluo Jiangu capsule;
adjuvant arthritis (AA);
anti-oxygen free radical;
anti-inflammatory
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects and possible mechanism of Huoluo Jiangu Capsule (HJC) on adjuvant arthritis rats. Methods The arthritic model of rats induced by Freund’s complete adjuvant was used in experiment. The effect of HJC on swelling degree of feet, weight of thymuse and spleen of AA rats were observed. The serum activity of SOD, GSH-Px and content of NO, MDA were determined. Results HJC can relieve swelling degree of feet and weight of spleen of AA rats, increase serum SOD, GSH-Px and decrease serum NO, MDA of AA rats. Conclusion HJC has good effet of cleaning up the oxygen free radicals and anti-inflammatory.
