Proliferation inhibition and apoptosis inducement of resveratrol on U251 cells
- VernacularTitle:白藜芦醇抑制人脑胶质瘤U251细胞增殖及诱导其凋亡的实验研究
- Author:
Hongsheng LIU
;
Jinhuan WANG
;
Xinn XU
;
Shujie WANG
;
Jianbin QI
;
Hongli LIU
- Publication Type:Journal Article
- Keywords:
resveratrol;
glioma cell of U251;
apoptosis
- From:
Chinese Traditional and Herbal Drugs
1994;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of resveratrol on inhibiting proliferation and inducing apoptosis of U251 cells. Methods The proliferation activity was detected by MTT assay, and apoptosis of early and late period by method of Annexin V-FITC apoptosis assay, and the cell morphological changes were observed by microscopy after U251 cells being treated with resveratrol. Results Resveratrol could significantly inhibite the proliferation and induce the apoptosis of early and late period of U251 cell in a time-and does-dependent manner. Conclusion Resveratrol can significantly inhibite the proliferation and induce the apoptosis of early and late period of U251 cell.
