Clinical Observation on Shen'ankang Granules for Chronic Renal Failure
- VernacularTitle:肾安康冲剂治疗慢性肾功能衰竭的临床研究
- Author:
Shaowei XIANG
;
Guodong HUANG
;
Shenchang LAI
- Publication Type:Journal Article
- Keywords:
RENAL FAILURE,CHRONIC/TCM-WM therapy;
SHEN'ANKANG GRANULES/therapeutic use;
ACTIVATING BLOOD AND PURGING TURBIDITY;
WARMING AND TONIFYING SPLEEN AND KIDNEY
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2000;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】To observe the therapeutic effect of Shen'ankang Granules(SG)for chronic renal failure(CRF)and to explore its therapeutic mechanism.【Methods】 Seventy-two CRF patients were equally randomized into groups A and B.The two groups were given oral use of Medicinal Charcoal Tablets and routine supportive and symptomatic treatment,and group A was given SG(mainly composed of Radix Astragali,Radix et Rhizoma Rhei,Herba Epimedii,Radix Notoginseng and Rhizoma Curcumae)additionally.The treatment lasted 8 weeks.The therapeutic effect in the two groups was compared after treatment.Meanwhile,the changes of blood urea nitrogen(BUN),serum creatine(SCr),endogenous creatine clearance rate(Ccr),urinary ?_2 microglobulin(?_2-M)and ?-N-acetyglucosamidase(NAG),as well as changes of serum fibrosis-associated proteins of type Ⅳ collagen(C-Ⅳ),type Ⅲ precollagen(PC-Ⅲ)and laminin(LN)levels were detected.【Results】The total therapeutic effect was 86.11% in group A,higher than 61.11% in group B(P0.05).The differences of serum C-Ⅳ,PC-Ⅲ and LN levels were significant between groups A and B(P
