Investigation of verapamil reverse the drug resistance of KBV200 cell line
- VernacularTitle:维拉帕米对喉癌细胞株耐药逆转作用研究
- Author:
Hongyan CHEN
- Publication Type:Journal Article
- Keywords:
Chemotherapetic agents;
KBV200 cell line;
MTT;
Verapamil
- From:
Journal of Chongqing Medical University
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To make a study of KBV200 cell line on its multidrug resistance and provide experimental data for clinical individual chemotherapy.Methods:MTT reduction assay was used to investgate the inhibition of 8 common chemotherapetic agents on KBV200 cell line.Result:Vincristine、Adriamycin、Bleomycin、Cyclophosphamide and Arabinosyl Cytosine have poorer inhibition than Harrihgtonine、Cicplatin and 5-Fu on KBV200 cell line.Conclusion:KBV200 cell line is multidrug resistance to Vincristine、Adriamycin、Bleomycin、Cyclophosphamide and Arabinosyl Cytosine.
