Current status, questions and challenges of transcatheter uterine artery embolization for the treatment of uterine fibroids
- VernacularTitle:全面认识子宫肌瘤导管栓塞治疗的现状、问题和挑战
- Author:
Xiaoming CHEN
;
Pengfei LUO
- Publication Type:Journal Article
- Keywords:
Uterine fibroid;
Embolization,therapeutic;
Following-up study
- From:
Journal of Interventional Radiology
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Current status, questions and challenges of transcatheter uterine artery embolization(UAE)in the treatment of uterine fibroids were summarized and analysed. It has been proved that UAE presents a good effectiveness in controlling the symptoms and shrinkage of fibroid and uterine volumes during follow-up of 4 to 6.9 years domestically and abroad, but relapse of the fibroid may however occur in 2 years or longer after UAE. Generally speaking,UAE is safe in the treatment of uterine fibroids but has a possibility of serious complications. UAE has no damage on normal uterine tissues but may affect pregnancy and delivery of patients significantly later on the cause of hypoxia and inertia of uterus. UAE may cause amenorrhea in the minority of women with ovarian failure and endometrium atrophy. The current questions are how to improve long-term efficiency to reduce relapse of tumor and to insure the safety of UAE. It is our further task to exploit more new effective and safe embolic agents by using animal and clinical study on the basic knowledge of pathology, pharmacology, biochemistry, endocrinology and molecular biology. (J Intervent Radiol, 2006, 15: 449-450)
