Changes and clinical significance of multi-organs dysfunctional indices during peri-operation period in patients with esophageal cancer at different altitude
- VernacularTitle:食管癌围术期多脏器功能指标在不同海拔地区的变化及意义
- Author:
Naibin LI
;
Shifan ZHANG
;
Yunjie WANG
- Publication Type:Journal Article
- Keywords:
Esophageal neoplasms Blood gas analysis Respiratory distress syndrome, adult Multiple organ failure Plain Plateau
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2003;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective Aims To investigate the dynamic changes of multi-organ functional indices in esophageal carcinoma patients during peri-operation period at flatland and moderate high altitude. Methods 44 cases of esophageal carcinoma scheduled to receive gastroesophagostomy were categorized semi-randomly into three groups: Flatland control group (FCG, n=8), moderate altitude lung protection group (MPG, n=16), moderate altitude control group (MCG, n=20). The cases in FCG and MCG underwent routine pulmonary function examination and respiratory tract preparation peri-operatively. Besides the above routine treatment, the cases in MTG received administration of Rahdiola compound capsules preoperatively, with 2 pills a day. Blood-gas and biochemical indices of multi-organs were recorded in the three groups preoperatively and at 1, 3, and 5 days postoperatively respectively. The patients' systematic reaction, the changing trend of the indices reflecting organs function and the postoperative complication were observed. Results The blood-gas parameters were different significantly both preoperatively and postoperatively between the three groups. While other indices reflecting the organs function were not different significantly between the three groups before the operation, but at 1, 3, 5 days postoperatively, the indices in MCG and MPG were significantly different with that in FCG (P
