Effect of Runingshuang on the Blood Rheology and Mammary Microcirculation of Rat with Cyclomastopathy
- VernacularTitle:乳宁霜对乳腺增生病大鼠血液流变学及乳房微循环的影响
- Author:
Aili SONG
;
Xiangqi LI
;
Yian SUN
- Publication Type:Journal Article
- Keywords:
cyclomastopathy;
microcirculation;
blood rheology;
Runingshuang;
experimental research
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To research the mechanism of treating cyclomastopathy with Runingshuang by measuring the blood rheology and mammary microcirculation. Methods 70 female Wistar rats of SPF were randomly divided into seven groups:the blank control group, the pathologic model group, the comparative group of tamoxifen ointment, the comparative group of Sanjierupi Glue, three remedial groups with large, middle and small dosage of Runingshuang. Pathologic model of mammary hyperplasia was made by injecting estrogen and progesterone. Except the former two groups, each group was treated with different drugs. The blood rheology and mammary microcirculation were measured after 30 days. Results Compared with the blank control group, blood viscosity, plasma viscosity, packed cell volume and the fibrinogen of the pathologic model group increased evidently (P
