Preparation of loganin and morroniside reference substances from Fructus Corni
- VernacularTitle:山茱萸中马钱苷和莫诺苷对照品的制备
- Author:
Xiaona LI
;
Changhong HUO
;
Wei YIN
;
Lantong ZHANG
- Publication Type:Journal Article
- Keywords:
Fructus Corni;
loganin;
morroniside;
reference substance;
preparation
- From:
Chinese Traditional and Herbal Drugs
1994;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish a separation method of loganin and morroniside reference substance from Fructus Corni. Methods After extracted with hot water and precipitated with alcohol, the extract of Fructus Corni was isolated and purified by macroporous resin, silica gel column chromatography, and preparative HPLC. Loganin and morroniside were identified by UV, 1H-NMR, 13C-NMR, and MS. Results The contents of loganin and morroniside was higher than 98% by normalization method of HPLC. Conclusion The developed method is simple with lower cost, by which loganin and morroniside can be used as reference substances for the qualitative and quantitative analysis of Chinese herbal medicine.
