Mechanism of Polysaccharide from Stigma Maydis for Diabetes Mellitus
- VernacularTitle:玉米须多糖治疗糖尿病作用机制的研究
- Author:
Juan LIU
;
Xiaoqiang HAN
;
Bo JIANG
- Publication Type:Journal Article
- Keywords:
Polysaccharide from stigma maydis;
Diabetes mellitus;
Tetraoxypyrimidine;
Blood sugar;
Glycogen;
Superoxyde dismutase;
Glutathione peroxidase
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the hypoglycemic effect of polysaccharide from stigma maydis and to explore its therapeutic mechanism preliminarily.Method The diabetes mice models were induced by tetraoxypyrimidine.The concentration of blood sugar was determined by glucose oxidase test.The influence of the stigma maydis polysaccharide on glycometabolism and its repair effect on damaged glycometabolism organs of diabetic mice were observed respectively by content determination of glycogen and by the measurement of activities of relative enzymes(superoxyde dismutase and glutathione peroxidase).Results The stigma maydis polysaccharide could decrease the blood sugar,promote the synthesis of glycogen and repair the damaged glycometabolism organs of diabetic mice.Conclusion The stigma maydis polysaccharide exhibits a good therapeutic effect on diabetic mice,and has a good development prospect.