Determination of Gallic Acid in Gongyanping Dispersible Tablet by HPLC
- VernacularTitle:HPLC法测定宫炎平分散片中没食子酸的含量
- Author:
Donghui LIU
;
Xingmiao GU
;
Dongsheng YUAN
;
Xinxin ZHOU
- Publication Type:Journal Article
- Keywords:
Gongyanping Dispersible Tablet;
Gallic acid;
HPLC;
Content determination
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish a method for the determination of gallic acid in Gongyanping Dispersible Tablet by HPLC.Method A HPLC method was performed on Hypersil ODS column(4.0?250 mm,5 ?m).The mobile phase was acetonitrile(0.2 %CH3OH)-water solution of 0.1 %triethylamine and 0.1 %phosphoric acid(1 ∶99).The detection wavelength was 220 nm and flow rate was 1.0 mL/min.Results Gallic acid showed a good linearity in the range of 0.022～0.352 ?g,r=0.999 9.The average recovery was 99.70 %,and RSD was 1.61 %.Conclusion This method is effective and can be used for the quality control of Gallic acid in Gongyanping Dispersible Tablet.
