Technology of Spray Pelletization for Compound Jiakang Tablets
- VernacularTitle:复方甲亢片的喷雾制粒工艺研究
- Author:
Guohua ZHENG
;
Qiufang CHEN
;
Fuliang XIONG
;
Wen LIU
- Publication Type:Journal Article
- Keywords:
Compound Jiakang Tablets;
Spray pelletization technology;
Orthogonal design
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To optimize the spray pelletization technology for Compound Jiakang Tablets.Methods The experiment was performed by orthogonal design,and the inspection criteria key were granule uniformity,granule size and the content of astragaloside IV,combined with the granule hygroscopic velocity.Results The optimal spray pelletization parameters were as follows:the frequency of main fan was(35.0?5)Hz,atomizational pressure was 0.1 mPa,the rate of spray was 1.2 Hz,the density of extract was 1.20 g/mL.Conclusion The granules made by this technology are uniform,burly,stable,and are beneficial for pressing into tablet.
