Experimental Study of Red Ceils Suspension in SAGS Solution:Ⅱ.Observation of Mutagenicity by Ames Method
- VernacularTitle:SAGS晶体盐红细胞悬液的实验研究——Ⅱ.Ames法的致突变研究
- Author:
Mingfu MA
- Publication Type:Journal Article
- From:
Chinese Journal of Blood Transfusion
1988;0(02):-
- CountryChina
- Language:Chinese
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Abstract:
A study of the mutagenieity of SAGS preservative solution for red cells,performed by Ames method, was reported.Result of the study in- dicated that there was no evidence of the positive mutagenicity reaction of SAGS preservative solution for red cells at its 6 doses ranging from 0.02 to 100mg/ml,whether the rat liver microsomal enzymes(S9)were added as metabolic activators or not.That is, the solution was unable to inducethe mutation at gene loci in the strains tested by Ames Method.
