Experimental Study of Suzijiangqi Decoction on Effect on the Relation between Passage Recombination and the Content of TNF and ET of Asthma Model
- VernacularTitle:苏子降气汤对哮喘大鼠气道重塑与肿瘤坏死因子、内皮素含量关系的影响
- Author:
Jianwei WANG
;
Jieyu ZHANG
;
Ji LI
- Publication Type:Journal Article
- Keywords:
Suzijiangqi decoction;
asthma;
passage recombination;
TNF;
ET
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the mechanism of Suzijiangqi decoction to passage recombination of asthma model by studying the effect of Suzijiangqi decoction on passage recombination and the relation between it and the content of TNF and ET of asthma model. Methods Asthma model was established by OVA atomized and inhaled, the effect of Suzijiangqi decoction on the lung histomorphometric and the content of TNF and ET in serum or plasma/BALF of asthma model were observed. Results Suzijiangqi decoction obviously improved the lung histomorphometric and significantly inhibited the content of TNF and ET. Conclusion Suzijiangqi decoction can obviously control passage recombination. It is relate to inhibiting the content of TNF and ET in serum or plasma/BALF of asthma model.
