Expression and significance of LRP and GST-?in the testis germ cell tumor
- VernacularTitle:LRP、GST-?在睾丸生殖细胞肿瘤中的表达及其意义
- Author:
Xiaoji LUO
- Publication Type:Journal Article
- Keywords:
The testicular germ cell tumor;
LRP;
GST-?
- From:
Journal of Chongqing Medical University
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the expression of LRP,GST-?in the testicular germ cell tumor and evaluate their role in multidrug resistance of the testicular germ cell tumor.Methods: 41 samples of germ cell tumor without chemotherapy were analyzed immunohistochemically.Results: The total positive percentage of LRP in the testicular germ cell tumor was 41.5%,the frequence of LRP expression in Ⅰ stage,Ⅱ+Ⅲ stage,seminoma and non-seminoma germ cell tumor was 23.1%,73.3%,40.0% and 45.5% respectively.There was significant difference of the LRP expression between I stage and Ⅱ+Ⅲ stage in the testis germ cell tumor(P0.05).Conclusion: The expression of LRP was correlational with the clinical stage of the testicular germ cell tumor,and LRP expression may be an important prediction of patients with testicular germ cell tumor.【
