Survivin expression in ovarian cancer and its associationwith tumor cellular apoptosis
- VernacularTitle:Survivin的表达与卵巢癌细胞凋亡的关系
- Author:
Wen SHU
- Publication Type:Journal Article
- Keywords:
Ovarian cancer;
Survivin;
Apoptosis
- From:
Journal of Chongqing Medical University
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate clinical significance of survivin expression,cellular apoptosis in ovarian cancer.Method: The apoptosis in sit ovarian cancer were identified by the terminal deoxynucleotidy transfer mediated dUTP-biotin nick end labeling(TUNEL) and survivin expression was detected by immunohistologic staining in 50 cases of ovarian cancer.Result: Survivin was expressed in 36 of 50 ovarian cancer(72%).The correlation was found between survivin expression,cellular apoptosis.The 5 year survival rate in the group of survivin-negative cases was significant higher than in the group of survivin-positive cases(P
