Evaluation of ~(153)Sm-EDTMP Therapy for Metastasis Prostate Cancer and Pain due to Bony Metastases after Hormone Therapy
- VernacularTitle:~(153)Sm-EDTMP治疗前列腺癌内分泌治疗后骨转移骨痛的效果评价
- Author:
Zhaobing TANG
- Publication Type:Journal Article
- Keywords:
Prostate cancer;
Bone metastases;
Bone pain 153Sm-EDTMP;
Hormone therapy
- From:
Journal of Chongqing Medical University
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To evaluate the effect of Samarium etramthylene phosphoric acid(153Sm-EDTMP) in the treatment of painful bony metastases from prostate cancer after hormone therapy.Methods: 18 patients after being treated with hormone therapy(excision of testes+flutamide) for 3~6 months and with painful bony metastases from prostate cancer were injected 153Sm-EDTMP(dosage:37MBq/kg),After the patients underwent 1~3 dose treatment.The palliation of pain and change of bone metastases on bone scans were evaluated.Results: A significant decrease of bone pain was achieved,making up 77.8%(14/18) and X ray and bone radionuclide imaging exam showed that 2 patients achieved complete focus disappearance,and 8 patients achieved partial focus disappearance.The response rate is 55.5%.Conclusion: 153Sm-EDTMP radiotherapy is efficacious to the refractory painful bone metastases in prostate cancer.
