Determination of psoralen and isopsoralen in Bushen Yinao Capsules
- VernacularTitle:补肾益脑胶囊中补骨脂素和异补骨脂素的含量测定
- Author:
Xuesong LI
;
Xingdong FAN
;
Zhubang YUAN
;
Changcheng ZHUO
;
Xiaolin LI
- Publication Type:Journal Article
- Keywords:
Bushen Yinao Capsules;
psoralen;
isopsoralen;
HPLC
- From:
Chinese Traditional Patent Medicine
1992;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To establish the method of determining psoralen and isopsoralen in Bushen Yinao Capsules(Fructus Psoraleae,Radix et Rhizoma Ginseng Rubra,Poria,etc.). METHODS: HPLC conditions were as(follows:) Chromasil C_(18) column,a mobile phase of CH_3OH-H_2O(55∶45),and the wavelength at 247 nm. RESULTS: This method showed a good linear relationship in the ranges of 0.038-0.309 ?g(psoralen) and 0.036-0.295 ?g(isopsoralen).The average recoveries were 99.50% for psoralen(RSD was 0.91%,n=5) and 100.52% for isopsoralen(RSD was 1.70%,n=5). CONCLUSION: The method is simple,swift,accurate and practical in quality control of Bushen Yinao Capsules.
