Effects of ?-asarone on the Expression of Endothelial Cell Adhesion Molecules Induced by Hypoxia and Reoxygenation
- VernacularTitle:?-细辛醚干预缺氧诱导的内皮细胞黏附分子表达的作用
- Author:
Yuping HE
;
Yong JIANG
;
Yongqi FANG
- Publication Type:Journal Article
- Keywords:
Cell adhesion molecule;
?-asarone;
Hypoxia-reoxygenation;
Flow cytometry
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of ?-asarone,the major constituent of Acorus tarinowii schott,on the expression of endothelial cell adhesion molecules induced by hypoxia and reoxygenation.Methods The expression rates of endothelial cell surface adhesion molecules VCAM-1 and CD62E were detected by flow cytometry(FCM) and specific labeled monoclonal antibody.Results Compared to the normal group,the expression rates of VCAM-1 and CD62E were increased significantly in the model group(hypoxia-reoxygenation group)(P
