A Case of Kallmann Syndrome Inherited in Autosomal Dominant Mode.
- Author:
Yoon Sung NAM
;
Sook Hwan LEE
;
Woo Sik LEE
;
Chan PARK
;
Jong Wook KIM
;
Kwang Yul CHA
- Publication Type:Case Report
- MeSH:
Aged;
Amenorrhea;
Fathers;
Female;
Humans;
Hypogonadism;
Kallmann Syndrome*;
Male;
Olfaction Disorders;
Pedigree;
Siblings;
Wills
- From:Korean Journal of Fertility and Sterility
1999;26(3):491-495
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: To report the pedigree of Kallmann syndrome inherited in autosomal dominant mode with variable expressivity. MATERIAL AND METHOD: Case report. RESULTS: The patient had amenorrhea and anosmia but did not have a sign of absolute hypogonadotropic hypogonadism. Her father had an anosmia and her two elderly sisters also had an anosmia but delivered babies uneventfully. Her two male siblings did not show any signs of hypogonadotropic hypogonadism. CONCLUSION: Kallmann syndrome has many different modes of inheritance such as autosomal dominant, autosomal recessive, and X-linked form. So the careful investigation of family pedigree is required.
