Determination of deoxyschizandrin and schisandrin B in Liganlong Tablet by HPLC
- VernacularTitle:HPLC测定利肝隆片中五味子甲素和五味子乙素含量
- Author:
Shaowa LV
;
Qingxia GUAN
;
Yongji LI
- Publication Type:Journal Article
- Keywords:
HPLC;
Liganlong Tablet;
deoxyschizandrin;
schisandrin B.
- From:
Chinese Traditional Patent Medicine
1992;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: A quantitative method was developed for the determination of deoxyschizandrin and schisandrin B in Liganlong Tablet(Fructus Schisandrae Chinensis,Radix Astragali,Radix Angelicae Sinensis,Radix et Rhizoma seucaulis Acanthopanacis Senticosi,etc.) by HPLC. METHODS: The chromatographic conditions included column Symmetry shield~(TM) RP_(18) 5 ?m,3.9 mm?150 mm,mobile phase: methanol-tetrahydrofuran-water(64∶4∶32),flow rate at 1 mL/min,wavelength at 220 nm. RESULTS: The number of theoretical plates is 3555.5.The Deoxyschizandrin liner is 0.068～0.340 ?g (r=0.999 9) and the Schisandrin liner range is 0.06～0.30 ?g (r=0.999 8).The resolutions are 5.09,1.12,respectively. CONCLUSION: The method is sensitive,quick and accurate for the determination of deoxyschizandrin and schisandrin B in Liganlong Tablet.
