Influence of Qingre Huayu Recipe(QHR) on Secretive Function of Vaso-endothelial Cells in Rabbits with Endotoxemia
- VernacularTitle:清热化瘀方对内毒素血症家兔血管内皮细胞分泌功能的影响
- Author:
Aidong YANG
;
Qingfa SHEN
;
Yongjie GUO
- Publication Type:Journal Article
- Keywords:
Qingre Huayu Recipe;
endotoxemia;
t-PA;
PAI;
ET;
NO;
TXB2;
6-Keto-PGF1?
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the mechanism of QHR (main ingredients:Gypsum, Anemarrhema Asphodeloides Bge, Paeonia Lactiflora Pall) on secretive function of vaso-endothelial cells in rabbits with of endotoxemia. Methods Endotoxemia model was induced by colibacillary endotoxin via auricular intravenous injection in rabbits. The changes on pathomorphology and secretive function of vaso-endothelial cells in the model and QHR group were observed. Results It showed the existence of microthrombus in the lung via microscope in the model. The balance destruction of t-PA/PAI, NO/ET, TXB2/6-K-PGF1? in the model (P