Effect of Pingchuanlingchongji on the Auricular Microcirculation in Mice
- VernacularTitle:平喘灵冲剂对小鼠耳廓微循环的影响
- Author:
Jintian LI
;
Yan GUO
;
Yongqi LIU
- Publication Type:Journal Article
- Keywords:
Pingchuanlingchongji;
mice;
microcirculation
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of Pingchuanlingchongji (PCL) on the auricular microcirculation of mice and to investigate the effect mechanism of the treatment for asthma. Methods 50 mice were randomly divided into five groups, group 1 and group 2 were given 0.9% NS (25 mL/kg) as control group; group 3 was given aspirin (0.25 g/kg), 4 group was given low-dose (1.1 g/kg) PCL, group 5 was given high-dose (2.2 g/kg) PCL. Last for seven days. We injected Posterior Pituitary Injection (0.5 U/mL) on the rear vein of 2-5 group mices after the last time of given druy. The diameter of micro-artery in mice auricular, the diameter of micro-vein and blood flow speed were observed. Results As compared with contral group, PCL could expand significantly the diameter of micro-artery and the diameter of micro-vein in mice auricular (P