Effects of Extracts of Securidaca Inappendiculata Hassk on Cultured Mouse Spleen Cell Proliferation and Secretion of Interleukin-2 and Tumor Necrosis Factor-?
- VernacularTitle:蝉翼藤对小鼠脾细胞体外增殖和淋巴因子分泌水平的影响
- Author:
Yongwen LI
;
Li LI
;
Zhifei LI
- Publication Type:Journal Article
- Keywords:
CYT;
lymphocyte proliferation reaction;
interleukin-2;
tumor necrosis factor-?
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of ethanol extracts of a Chinese medical herb stem and radix of Securidaca inappendiculata Iassk (CYT), on lymphocyte proliferation and secretion of interleukin-2 (IL-2) and tumor necrosis factor (TNF-?) of mouse spleen cells in vitro. Methods Different concentrations of ethanol extracts of CYT were added to mouse spleen cell cultures supplemented with ConA. Lymphocyte proliferation reaction was detected by MTT assay. IL-2 and TNF-? secreting level were measured by ELISA. Results Ethanol extract of Securidaca inappendiculata Hassk increased cultured mouse spleen cell proliferation and secretion of IL-2 and TNF-B in the presence of ConA. Conclusion Ethanol extracts of CYT could raise mouse lymphocyte activities in vitro.
