Fetal rats arrhythmias in intrahepatic cholestasis of pregnancy
- VernacularTitle:孕鼠肝内胆汁淤积症致胎鼠心律失常的实验研究
- Author:
Yong SHAO
- Publication Type:Journal Article
- Keywords:
Intrahepatic cholestasis of pregnancy;
Arrhythmias;
Sudden death
- From:
Journal of Chongqing Medical University
1986;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate fetal rats abnormal electrocardiograms in intrahepatic cholestasis of pregnancy(ICP).Methods: The animal model of intrahepatic cholestasis of pregnancy was induced by 17-?-Ethinylestradiol and Progesterone.The electrocardiograms of fetal rats by conceptual day 20th(Group1),day 21st(Group2) were evaluated with Powerlab biologic signal extracting and analyzing system Chart 5 Software.Results: ①The serum total bile acids(TBA) levels of pregnant rats of ICP were 64.3?5.2(?mol/L) in group 1,78.5?4.5(?mol/L) in group 2,respectively,which showed significant differences(P
