Influence of SSRIs(selective serotonin reuptake inhibitors)/citalopramon cognitive impairment in patients with stroke
- VernacularTitle:SSRIs/西酞普兰对卒中后认知功能障碍的影响
- Author:
Changyu CHEN
- Publication Type:Journal Article
- Keywords:
SSRIs;
Citalopram;
Cognitive impairment
- From:
Journal of Chongqing Medical University
1986;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the effect of early treatment with SSRIs/Citalopram on cognitive impairment in patients with stroke.Methods: A total of forty patients with cognitive impairment following stroke,in the Department of Neurology,Southwest Hospital of the Third Military Medical University,selected by the Mini-Mental State Examination,were randomly divided into treatment group and control group.All the patients received routine treatment,besides Citalopram were given to those in the treatment group.20mg Citalopram Hydrobromide Tablets would be given after breakfast everyday for 3 mouths?Patients in both groups were investigated with the Mini-Mental State Examination,Hamilton Rating Scale for Depression,National Institute of Health Stroke Scale and Barthel Index to examine the functions before and 1 and 3months after treatment respectively.Result: The improvement of cognitive function of patients in the treatment group was obviously superior to those in the control group(19.35?2.85,21.55?3.24,P
