Effect of Guanxin No. 1 Recipe for Coronary Heart Disease:An Observation of 48 Cases
- VernacularTitle:中药冠心一号方治疗冠心病48例临床研究
- Author:
Yong CHEN
- Publication Type:Journal Article
- Keywords:
CORONARY DISEASE/TCD therapy;
ANGINA PECTORIS/TCD therapy;
GUANXIN NO.1 RECIPE/therapeutic use;
INVIGORATING QI AND NOURISHING YIN;
ACTIVATING BLOOD AND REMOVING STASIS
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
1999;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective] To investigate the therapeutic effect of Guanxin No. 1 Recipe (mainly composed of Radix Codonopsis, Radix Ophiopogonis, Fructus Schisandrae Chinensis, Rhizoma Polygonati Odorati, Rhizoma Chuanxiong, Rhizoma Anemarrhenae, Radix Salviae Miltiorrhizae, Radix Notoginseng, Radix Curcumae) for coronary heart disease (CHD) with angina pectoris (AP) and to observe its influence on blood lipid and hemorrheology indexes. [Methods] Eighty-eight patients with AP were allocated to group A (n = 48) and group B (n = 40) according to random number table. The two groups were given isosorbide dinitrate, Metoprolol Tartrate Tablets and enteric-coated aspirin tablets, and group A was treated with Guanxin No. 1 Recipe additionally. Four weeks constituted one treatment course. The effects on TCM syndromes, AP, electrocardiogram (ECG) and symptoms scoring, as well as on blood lipid level and hemorrheology indexes were observed before and after treatment. [Results] After treatment, the effects on TCM syndromes, AP, electrocardiogram and symptoms scoring in group A were superior to those in group B (P 0.05) . Whole blood high-shear viscosity (WBHSV) and whole blood low-shear viscosity (WBLSV) were decreased in the two groups (P 0.05). [Conclusion] Guanxin No. 1 Recipe has a better effect on relieving symptoms and improving EGG in CHD with AP, and this may be related to the decrease of blood lipid level and improvement of hemorrheology index.
