Clinical Observation on Huangqi Injection in Inhibiting the Side Effects Induced by Chemotherapy
- VernacularTitle:黄芪注射液对化疗副作用的拮抗作用的临床观察
- Author:
Meiying LIN
;
Ying GUAN
;
Encun HOU
- Publication Type:Journal Article
- Keywords:
LEUKEMIA, MYELOGENOUS/drug therapy;
TUMOR COMBINED CHEMOTHERAPY REGIMEN/adverse effects;
RADIX ASTRAGALI/therapeutic use;
RADIX ASTRAGALI/immunology;
IMMUNOGLOBULINS/drug effects;
COMPLEMENTS C3/drug effects
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
1999;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective] To observe the regulatory effect of Huangqi Injection (HI) on immune function of patients after chemotherapy (CT). [Methods] Thirty-four patients confirmed as acute myelogenous leukemia (AML) received two cycles of CT. During the 1st cycle, the patients were only treated with DA (daunomycin + arabinoside) regimen; in the 2nd cycle, intravenous injection of 20 mL of HI, qd for 2 weeks was added. The effect of CT on myelosuppression and immune function of the patients was observed. [Results] Immunosuppressive manifestations such as myelosuppression, fatigue, spontaneous sweating, impaired appetite, lassitude were found after the 1st cycle of CT, and peripheral immunoglobulin A (IgA), IgG, IgM and complements C3 levels were also decreased (P