Effect of Shenmai Injection on the expression of bFGF and PCNA in tumor
- VernacularTitle:参麦注射液对胃癌中bFGF、PCNA基因表达的影响
- Author:
Li XU
;
Zhishan DING
;
Yinghui WEI
;
Nipi CHEN
;
Chengxian GAO
- Publication Type:Journal Article
- Keywords:
Shenmai Injection;
basic fibloblast growth factor;
proliferating cell nuclear antigen;
gastric cancer;
angiogenesis;
mouse
- From:
Chinese Traditional Patent Medicine
1992;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate the effect of Shenmai Injection on the expression of bFGF and PCNA of gastric cancer in mouse. METHODS: RT-PCR was used to measure the expression of bFGF and PCNA in gastric cancer cell cultured with Shenmai Injection in three concentrations.immunohistochemistry used for protein synthesis in mouse gastric cancer model. RESULTS: 140 ?L/mL of Shenmai Injection concentration inhibited 63% of bFGF and PCNA gene expression. CONCLUSION: Shenmai Injection can inhibit the express of bFGF and PCNA.
