Interstitial lung disease in patients with Sjgren′s syndrome
- VernacularTitle:原发性和继发性干燥综合征肺间质病变的临床分析
- Author:
Yongfeng ZHANG
;
Yuewu LU
;
Xi CHEN
;
Yi ZHENG
- Publication Type:Journal Article
- Keywords:
Sjgren′s syndrome;
Lung diseases, interstitial;
Tomography, X-ray computed;
Anti-SSA antibody
- From:
Chinese Journal of Rheumatology
2001;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the prevalence and clinical characteristics of Sj?gren′s syndrome-interstitial lung disease (SS-ILD). Methods 136 patients with SS were studied. Anti-SSA and Anti-SSB antibodies were measured by Western blot. The inpatients had chest X ray, chest HRCT and pulmonary function examined. Results ①pSS-ILD patients with postive anti-SSA antibody were proned to have interstitial lung disease and the ILD were more severe. ②HRCT showed that sSS-ILD were more severe than that of pSS-ILD. ③Lung capacity of pSS-ILD decreased more frequently than sSS-ILD. sSS-ILD mainly had venti-latory function abnormalities. The lung function impairment of both were dominated by small airways dysfunction and decrease of TLCO. Conclusion SS patients should be examined by HRCT and lung function tests should be performed in the course of the disease to find out and treat ILD.
