Experimental Studies on the Effects of Baicalin and Berberine against Trichomonas Vaginalis in Vitro
- VernacularTitle:黄芩苷、黄连素体外杀灭阴道毛滴虫的实验研究
- Author:
Jing YANG
;
Yingyuan FU
- Publication Type:Journal Article
- Keywords:
Baicalin;
Berberine;
Trichomonas vaginalis;
minimal lethal concentration
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objectives To explore the effects of Baicalin and Berberine against Trichomonas vaginalis(TV) in vitro. Methods The micro-double-dillution assay is used to measure the Minimal lethal concentration (MLC) of Baicalin and Berberine against 6 freshly isolated strains of TV, using metronidazole as control. Results MLC of Baicalin and Berberine against 6 isolated strains in vitro of TV ranges from 0.125 to 0.5 mg/mL and 0.25 to 1.0 mg/mL, respectively. The means of MLC are 0.229 mg/mL and 0.417mg/mL, respetively, with statistically significant difference (t=2.666, P