Activity of NF-?B in patients after cardiopulmonary resuscitation and its response to Ulinastain
- VernacularTitle:心肺复苏患者血浆核因子?B的变化及乌司他丁的保护作用
- Author:
Xiaoli JING
;
Dongping WANG
;
Xin LI
;
Xiaoxing LIAO
;
Zhongfu MA
- Publication Type:Journal Article
- Keywords:
CPR;
NF-?B;
Ulinastain;
Protection
- From:
Chinese Journal of Emergency Medicine
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the incidence of systemic inflammatory response syndrome(SIRS) after cardiopulmonary resuscitation(CPR) and to observe the effect of Ulinastain in inhibition of inflammatory mediator.Methods Forty patients surviving more than 48 hours after CPR were divided into Ulinastain and control groups randomly. Activity of nuclear factor kappa B(NF-?B), IL-6,TNF-? of the patients was detected .All patients were evaluated by SIRS diagnosis standard and their general organ function was examined. All data were compared between two groups.Results Activities of NF-?B, IL-6,TNF-? of patients after CPR was significantly higher than that of normal people (P
