Comparison of the Effect of Polysaccharides from Rhizoma Dioscoreae and Rhizoma Dioscoreae Preparata on Immune Function in Mice
- VernacularTitle:山药及其麸炒品的多糖部位对小鼠免疫功能的影响
- Author:
Lin CHENG
;
Bin CHEN
;
Baochang CAI
- Publication Type:Journal Article
- Keywords:
Rhizoma Dioscoreae;
Rhizoma Dioscoreae Preparata;
Polysaccharides;
Carbon clearance;
Hemolysin
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the immunoregulatory role of polysaccharides from Rhizoma Dioscoreae and Rhizoma Dioscoreae Preparata in mice with immunosuppression. Methods Carbon clearance test and hemolysin test were used to evaluate the non-specific and specific immunoregulatory roles of polysaccharides from Rhizoma Dioscoreae and Rhizoma Dioscoreae Preparata by different extraction methods..Result The polysaccharides extracted with cold water from Rhizoma Dioscoreae Preparata had a stronger effect than Rhizoma Dioscoreae on increasing the index of K and enhancing phagocytic function of mononuclear-macrophage and hemolysin level. Conclusion The polysaccharides extracted with cold water from Rhizoma Dioscoreae Preparata have a stronger effect in improving the cellular and humoral immune function than Rhizoma Dioscoreae, which accords with the clinical application and will lay a foundation for further explaining the processing mechanism of Rhizoma Dioscoreae Preparata.
