Effect of Tianma Gouteng Decoction on Myocardial Fibrosis in Renovascular Hypertensive Rats
- VernacularTitle:天麻钩藤饮对肾血管性高血压大鼠心肌纤维化的影响
- Author:
Shiyun HU
;
Shaoxiang XIAN
;
Licheng ZHAO
;
Nanyi LI
- Publication Type:Journal Article
- Keywords:
Tianma Gouteng Decoction;
Renovascular hypertension;
Myocardial fibrosis
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of Tianma Gouteng Decoction on myocardial fibrosis in renovascular hypertensive rat (RHR). Methods RHR models were established by occlusion of renal artery with artery forceps. The collagen concentration and the contents of collagen type I,III were measured. Meanwhile, the weight of heart and left ventricle was determined. Results (1)Both Tianma Gouteng Decoction and Captopril could reduce the left ventricle weight index (LVI) and collagen contents (P
