Method Evaluation of HPLC Fingerprints for Quality Control of Chinese Herbal Medicine
- VernacularTitle:指纹图谱评价中药质量的方法学考证
- Author:
Lijun NI
;
Jia GUO
;
Xiaohong ZENG
;
Liguo ZHANG
- Publication Type:Journal Article
- Keywords:
Chromatogram fingerprint of Chinese herbal medicine;
Peak area ratio;
Peak area quantification;
Similarity coefficient;
HPLC;
Quality evatuation of TCM
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of different chromatogram fingerprints analysis methods on the quality evaluation of Chinese herbal medicine. Methods With the chromatogram fingerprints of a Chinese patent medicine in different batches as the analytic object, the quality evaluation of three methods such as peak area ratio,peak area quantification and similarity coefficient were investigated. Results The method of peak area ratio has the highest accuracy rate and the precise rate for quality evaluation, and similarity coefficient and peak area quantification came next. The result of peak area quantification was similar to that by current evaluation method. Conclusion Different chromatogram fingerprints analysis methods would result in a great difference in the quality evaluation of Chinese herbal medicine.
