A Case fo Toxic Epidermal Necrolysis.
- Author:
Oh Jin KWON
;
Jung Hee SUH
;
Joon Young SONG
- Publication Type:Original Article
- MeSH:
Anti-Bacterial Agents;
Debridement;
Epidermis;
Hepatic Encephalopathy;
Hospitalization;
Humans;
Male;
Middle Aged;
Odors;
Sepsis;
Skin;
Stevens-Johnson Syndrome*;
Tetanus
- From:Korean Journal of Dermatology
1980;18(5):465-469
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A case of toxic epidermal necrolysis (TEN) was presented in 46 year-old male patient. The characteristic skin lesions of TEN were developed after some medictions and tetanus anti-toxin (TAT) injection due to trauma. Probably, the cause of the disease was drugs, TAT injection or trauma inself. On the pathologic findings, lower epidermis and dermo-epidermal cleavage were noticed. He was treated with massive antibiotics and steroid. About 7 days after therapy, much improvement achived. However foul odorous yellowish discharge was noticed since 20 days of hospitalization. Wide debridement of necrotic tissue was carried without improvement. Patient expired on 48th hospital day due to sepsis and impending hepatic coma.