Study on the supercritical CO_2 extraction of curcumolin Curcuma with uniform design and regression analysis
- VernacularTitle:均匀设计和回归分析优选莪术超临界萃取工艺
- Author:
Hongmei LIU
;
Keyi LI
- Publication Type:Journal Article
- Keywords:
supercritical extraction;
curcumol;
uniform design;
regression analysis;
path analysis
- From:
Chinese Traditional Patent Medicine
1992;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To optimize the extraction process for the active components in Curcuma by supercritical CO_2 as guided by the contents of curcumol in Curcuma. METHODS: Gas chromatography was used to determine the contents of curcumol in the extract.Uniform design and path analysis were used to optimize SFE process. RESULTS: The optimum process was established as following:20 MPa as extracting pressure,40℃ as extracting temperature,120 minutes as dynamic extracting time and 20 minutes as static extracting time,24 mL of 70% alcohol as modifier.The absolute error of the predicted value from the model was smaller than 0.6%. CONCLUSION: The regression model is very notable and reasonable and can forecast results precisely.
