The Effect of Ganzhixiao Granule on the Kuffer Cell Function of Fatty Liver Rat
- VernacularTitle:肝脂消颗粒剂对脂肪肝大鼠肝微粒体、线粒体脂质过氧化损伤的影响
- Author:
Zhigang DONG
;
Xiaoyan MA
;
Chengjun GONG
- Publication Type:Journal Article
- Keywords:
fatty liver;
Ganzhixiao granule;
kuffer cell cytokine
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective Rereach into the pharmaceutical mechnisms of Ganzhixiao Granule which is used to treat fatty liver. Method Build up fatty cirrhosis-rat models by feeding with high-fat food and alcohol. Contract with Dongbaogantai and observe the influence of Ganzhixiao granule on SOD, MDA and the liver function ferment. Result In the group of Ganzhixiao, the activeness of the liver’s SOD can be increased, while the content of MDA and the activeness of ALT and AST can be decreased, that is much better than Dongbaogantai. Conclusion Ganzhixiao granule has strong effect on fatty cirrhosis, and its mechanism may be concerned with the rat’s liver cell membrane and restraining damaging kuffer cell cytokine.
