Inhibition of Smilax Glabra Roxb on VCAM-1 Expression Induced by IL-1 of Human Vascular Endothelial Cells
- VernacularTitle:土茯苓对白细胞介素-1诱导的血管细胞粘附分子-1表达的影响
- Author:
Xiulan HUANG
;
Xuejing ZHANG
;
Wei WANG
- Publication Type:Journal Article
- Keywords:
Smilax Glabra Roxb;
human vascular endothelial cells;
VCAM-1
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the protective effect of Smilax Glabra Roxb on the expression of vascular cell adhesion molecule-1 (VCAM-1) induced by IL-1 in human vascular endothelial cells (HUVECs). Methods Take human umbilical vascular endothelial cells as study subject, use immunofluorescence staining, serum pharmacology of the traditional Chinese medicine and flow cytometer. The level of VCAM-1 is represented by the mean fluorescence intensity. Results IL-1 increases the expression of VCAM-1, the expression of VCAM-1 in group of serum containing drugs is lower than control group. Conclusion Smilax Glabra Roxb can inhibit the effect of IL-1 induced increase of VCAM-1 expression in HUVECs.
